Group Contribution Method

GCM (Group Contribution Method) estimates the standard Gibbs free energy of formation (ΔfG’°) and reaction (ΔrG’°) in biochemical systems, based on the group contribution method developed by Mavrovouniotis. Our online tool allows the user to enter a molecule of interest (format: molfile) and to retrieve the estimated ΔfG’° including the standard error.